Monnier Root is a pro-erectile herb in Traditional Chinese Medicine. Its main bioactive component, known as "osthole", has a similar effect to Viagra on the penile tissue and hippocampus. The effects of Root Monnier on testosterone and cognition remain unexplored.

Reference

Also known as:

Shi Zhuang Tzu, osthol, Jashoshi, zhgun-root fruits

Not to be confused with:

Bacopa monnier, officinalis root (similar but separate plants)

Useful information:

osthole, the main bioactive component of the Monnier root, does not dissolve in water; it is recommended to consume either an ethanolic extract of the fruits of the squash root, or at least add it to food

Variety:

Aphrodisiac

Traditional Chinese Medicine

Pairs badly with: Viagra as part of sildenafil (they do not neutralize each other, but they act the same, moreover, they do not complement each other in any way; taking both at once is a waste of money)

Origin and Composition

Origin

Monnier Root is used in Traditional Chinese Medicine. The plant itself is called Monnier Root Root, its taproot is called Root Root Rhizome, and the seeds are called Shi Zhuang Tzu, or, in Japanese, Jashoshi. The fruits of the plant are used in traditional Chinese medicine to treat skin and acne, as an antiviral drug, an aphrodisiac (for men), a gynecological drug (for women), as well as an anti-osteoporosis, anti-diabetic and sometimes even as an anti-inflammatory drug. Occasionally, and without any scientific basis, one can even hear vague claims that this plant can also prevent aging and promote strengthening of the body.

Composition and structure

Root Monnier contains: Coumarin compounds such as osthole (18.85-20.12mg/g in dry fruit) and emperorin (0.79-1.02mg/g), as well as Xanthotoxin (Methoxalene). Isopimpinelin and bergapten were also found in the composition. The dried fruits of the zhgun-root contain from 1.67 to 2.88% of osthole.

Osthole is the main bioactive component of the plant due to the fact that it is the most isolated derivative of coumarin and its compound in the Monnier fire root. its chemical name is 7-methoxy-8(3-methylpent 2-enyl)coumarin and its structure is shown below. In Traditional Chinese Medicine, the fruits of the plant are used, but the bioactive components are also found in its seeds. Due to the presence of an additional pentanuclear ring in imperatorina, this compound is regarded as furanocoumarin. It's still coumarin, just the next step in the classification. Osthole is poorly soluble in water, making it difficult to isolate. Root Monnier contains coumarin compounds similar in their action to osthole, which is considered the main bioactive component of the plant. The concentration of these compounds in dried fruits can be quite high. It should be noted that osthole can also be found in the plant Angelica fluffy, and it was first isolated from nasturtium mustard (Peucedanum ostruthium), from which it got its name.

related herbs

Zhgun-root officinalis is a traditional analogue of Monnier's zhgun-root in Chinese and Korean medicine, in Korean its name is Chon-Gun. This plant is known for its "oriental" taste and smell and contains various essential oils. It is a perennial herb from the Apiaceae family, used medicinally as a sedative, as well as to treat anemia, brain disorders, and inflammatory conditions of the female genitalia, such as menstrual disorders. The composition of the zhgun-root officinalis includes:

Ferulic acid (ethanol extract of rhizome) - from 0.69 to 1.65 mg / g

Chlorogenic acid (ethanol extract of rhizome) - from 0.84 to 5.35 mg / g

Phthalide Senkinolide A ranging from 0.32mg/g (+/-0.02) to 1.14mg/g (+/-0.06) and Z-ligustilide (ethanol extract of rhizome) from 0.74mg/g (+/-0.04) to 4.39 mg/g (+/-0.31) (mean values, based on the results of a study of 15 herbs, were 0.65 mg/g and 1.56 mg/g, respectively). Other phthalides are also present in the composition, for example, Senkinolide H and 6-hydroxy-7-methoxy-dihydroligustilide.

Falcarindiol (heptadeca-1,9(cis)-diene-4,6-dien-3,8-ol), as well as an anti-inflammatory molecule with an IC50 = 4.31 ± 5.22µm, which is responsible for the inhibition of nitric oxide from LPS-stimulated macrophages.

Pharmacology

Absorption and serum

Mice were orally injected with 40mg/kg osthole, then using micellar extraction, the following results were obtained: Cmax = 2.72 ± 0.89μg/mL at Tmax = 0.56 ± 0.18 hours, AUC = 11.27 ± 2.63μg/h/mL and AUC0-t = 10.49 ± 2.81 µg/h/ml, and the half-life was 5.26 ± 1.67 hours. The only parameter that significantly differed between oral and intravenous administration of the drug was Tmax (significant difference, 0.093 hours intravenously) and slightly Cmax, due to the excellent bioavailability of injections. Discharge dynamics were not measured in this study. It was decided to use hollow fiber liquid phase microextraction + HPLC (which presumably gives more reliable results than micellar extraction) resulting in 20mg/kg osthole administered orally giving Cmax = 366 ± 89ng/mL at Tmax = 0.61 ± 0.09 hours, AUC0-t = 780 ± 585 ng / h / ml, and the half-life was 4.94 ± 1.84 hours. Oral administration of 40mg/kg of the drug gave AUC = 11.27 ± 2.63mcg/h/mL and Cmax = 2.72 ± 0.89mcg/mL, while injections of 8mg/kg gave AUC = 10.52 ± 2.34mcg/h/mL and Cmax of 4.35 ± 0.65 µg/ml, which allows to derive an average bioavailability of 26.8% when administered to rats. Bioavailability may be limited by metabolism, which was confirmed in vitro when 80% of osthole was metabolized within 20 minutes and 40% within 5 minutes of contact with intestinal cells via first-stage conjugation. By itself, osthole does not have a high permeability through intestinal cell membranes through passive diffusion, and apical value to basal-lateral has approximately the same ratio as basal-lateral to apical diffusion. Supporting the claim that passive diffusion is an uptake mechanism is the fact that MRP inhibitors have no effect on kinetics and the diffusion process does not appear to be temperature dependent (neutralization of transport enzymes). Once isolated, osthole has a moderate bioavailability (not the best, but quite high compared to other plant-derived components), as well as a relatively fast Tmax, which jumps in the blood within an hour after oral administration. Although one study reported values ​​in micrograms and the other in nanograms, this difference is only due to different approaches to analysis. When using an ethanolic extract of the fruit of the chai root (dried and washed twice in ethanol, followed by the introduction of the resulting concentrate), 10g/kg of this drug (total - 131mg/kg of osthole) administered to mice gives a similar Tmax (1 +/ - 0. 3 hours), as well as a half-life (3.6 +/- 0.6 hours), AUC = 3.55 ± 0.385 μg / h / ml, and Cmax = 0.776 ± 0.069 μg / ml. Ostol, used in the composition of Bukhtarma Rosemary, has less absorption than isolated ostol. In contrast to the fruit of Evodia leatherosperm, the use of osthole through an ethanol extract from the fruit does not increase the bioavailability of this component. In theory, it is capable, but the use of the fetus is not necessary.

Metabolism

Metabolism via demethylation (to O-demethyl osthole) may be facilitated by CYP2D6 or CYP3A4, but in vitro inhibition of CYP2D6 with Yohimbine had no effect on hepatic metabolism of osthole. Inhibition of CYP3A4 appears to increase the half-life in vitro, despite the fact that the aforementioned metabolites are O-demethylated and not N-demethylated. However, these in vitro results differ from those obtained in vivo rats, suggesting that hydroxylation, demethylation, and hydrogenation of double bonds were the major metabolic pathways during the first step. Osthole's low bioavailability is largely due to excessive and too rapid first-stage metabolism, and metabolism itself has multiple pathways.

Excretion from the body

After oral administration of 20 mg/kg osthole, the immune clearance index was 0.67 ± 0.15 ml/kg/h.

Interaction with the liver

Fatty infiltration of the liver

Osthole can reduce fatty liver caused by alcohol; in the study, mice were fed 52% ethanol for 4 weeks and then fed 10-40mg/kg osthole for 6 weeks. The drug normalized changes in the degree of transcription of CPT1A and CYP2E1 (which was disturbed by prolonged administration of alcohol, which provoked further accumulation of fat), and also lowered the fat content in the liver. A similar effect is exerted by the same dosage of osthole when administered together with antioxidant and anti-inflammatory drugs, although osthole appears to promote the activation of rAPP, which in turn reduces the activity of DGAT and HMG-CoA, i.e. this process contributes to the activation of lipids rather than their accumulation. Minimal dose dependence is observed - a higher dose of osthole has a greater protective effect, and 10 mg / kg is considered ideal ratio cost/efficiency. A positive effect is also exerted on the fatty infiltration of the liver caused by a diet, especially enriched in milk fat. The cause of fatty infiltration of the liver is not so important, only the presence of fatty acids in principle plays a role. In one study, subjects were given 10-40mg/kg osthole for six weeks, followed by full-fat milk for 2 weeks, and it was found that triglyceride levels in liver tissue dropped even below baseline. Osthole, the active component of the Monnieri root, is able to lower the level of triglyceride in the liver (in case of fatty infiltration) elevated due to both excessive alcohol consumption and too fatty foods. Studies in humans have not been conducted, but there have been inconclusive studies in rats. The above described mechanism of activation of rAPP against the background of alcohol-induced fatty infiltration of the liver was also observed in the case of the same hepatosis provoked by fatty foods (NAFLD), then rAPP reduces excessively elevated as a result of this liver condition indicators of DGAT and CYP7A1, and also increases the activity of suppressed CPT1A. An independent alternative mechanism is the modulation of SREBP-1c/2 proteins, in which 10-40mg/kg of osthole suppress SREBP-1c and SREBP-2 mRNA in mice suffering from fatty liver by 36.6%–54.6% and 64.5%–107.7%, respectively. , and 40mg/kg osthole normalizes SREBP-2 to baseline. The degree of transcription of fatty acid synthase mRNA decreases by 9.1%–38.7%, and that of LDL receptors by 54.7%–78.9% after administration of 10–40 mg/kg of osthole to the liver of experimental rats. It is not known whether this occurs against the background of BSSRE modulation or rAPP activation. Two unique mechanisms of action have been studied for their ability to interact with osthole and both either clear fatty acids from the liver or use them for energy.

Protection

In vitro, monnier root has been injected into human liver cells to neutralize the effects of tacrine through torilin components. As shown by the EC50 values, Torilin and Torilolone protect liver cells from the effects of tacrine 3.34 and 19.1 times more effectively than silybin, which is part of Milk Thistle.

Diabetes

Although osthole (part of the cauliflower root) is considered an AMPK activator that may reduce the effects of diabetes on the body (see section on glucose metabolism), lowering liver fat may also help control diabetes. Interaction with cancer cells

general information

Osthole has a non-selective cytotoxic effect on cancer cells, especially breast cancer (MCF-7), lung (SK-LU-1), liver (HepG2) and epidermal carcinoma (KB) cells.

breast cancer

In laboratory studies of cell lines MCF-7 and MDA-MB-231, it was found that osthole is able to inhibit the proliferation of cancer cells in breast cancer with an IC value of 25.8 μm and 30.2 μm, respectively. The inhibition is moderately effective. A possible mechanism of action for this cytotoxicity may be the inhibition of fatty acid synthase, which causes cytotoxicity of the precursors. Osthole also has a cytotoxic effect on HER2-producing cells, which increases the activity of fatty acid synthase. This provokes a decrease in Akt / mTOR inhibition in breast cancer cells, since HER2 acts through them on fatty acid synthase, and this suggests that osthole has the same mechanism of action as green tea catechins. The fatty acid synthase phenotype is typical in breast cancer, at least 30% (according to the results of the analysis of HER2). MPM2 inhibition was also observed in laboratory studies of osthole, which explains the ability of the drug to suppress the invasion and metastasis of breast cancer cells. It is likely that this process is related to fatty acid synthase, since cells that produce HER2 in excess of the norm are usually more prone to metastasis. Potentially, it can fight breast cancer, but studies in a living body have not been conducted. Affects fatty acid synthase and Akt/mTOR in much the same way as green tea catechins, however comparative analysis efficiency is impossible.

Neurology

Glutaminergic neurotransmission

Under laboratory conditions, isolated osthole (a bioactive component of the Monnier root) and hippocampal cells together increase the production of glutamate from neurons during an action potential (AP) from 7.9 ± 0.2 nmol / mg every 5 minutes (without osthole) to 11.7 ± 0.5 nmol / mg every 5 minutes (3µm osthole, 48.1% increase) without any effect on normal glutamate production. The same effect is achieved with the use of Imperatorin, another bioactive element. The IC50 for this reaction was 3.5 µm (4.7 µm imperatorin) and did not depend on the drug concentration. The mechanism of action is mediated by influx of Ca2+ into neurons during PD, while osthole, at a concentration of 3 µm, increases the maximum level of Ca2+ from 138.3±3.1 nmol (PD, without osthole) to 159.5±2.3 nmol (3 µm osthole) and acts by activating the PKC, as PKC phosphorylation rises from 112.5+/-3.8% (PD, no osthole) to 134.6+/-5% (3µm osthole during PD). Osthole does not affect the residual potential of the membrane. In vivo studies, cGMP neurotransmission accelerated not only glutaminergic neurotransmission, but also the accumulation of cGMP itself, a molecule that accelerates PKC neurotransmission. This is facilitated by inhibition of cGMP protein kinase (cGMP-dependent protein kinase, or PCD), which also prevents the release of glutamate from osthole. Activation of cGMP can cause all of the above processes, and incubation of neurons with Viagra (sildenafil) can increase cGMP (through PDE5 inhibition), making it appear that the osthole has already begun its action. Sildenafil and osthole appear to be similarly effective given EC50s of 5uM and 4uM, respectively. Two other cGMP activators and no additional effects of osthole were also found. These results suggest that Osthole and Viagra have similar mechanisms of action, but do not complement or enhance each other's action. In addition to enhancing Ca2+ influx and pre-axonal effects of cGMP, osthole (as well as imperatorin) can also enhance exocytosis of glutaminergic vesicles, which promotes active release of glutamate. Increased exocytosis of vesicles is caused by Ca2+ influx, while inhibition of this influx prevents a similar result. An increase in hippocampal glutaminergic neurotransmission may explain the proerectile effects of cauterine root (see section on sexuality), as glutaminergic processes in the hippocampus are associated with erection. Once injected into the hippocampus or hypothalamus, glutamate agonists induce an erection that is neutralized by glutamate receptor antagonists. During erection, increased levels of glutamate are also observed in the cerebrospinal fluid and hypothalamus. Increases glutaminergic neurotransmission by increasing calcium influx into neurons during an action potential. This is due to an increase in the level of cGMP in neurons. The process can be localized in the hippocampus and some other areas of the brain, such as the hypothalamus. This mechanism of action suggests that it is able to enhance neural stimulation without being a stimulant in itself.

Sedation and GABA neurotransmission

Osthole enhances sedation under the influence of phenobarbitol, and also relieves hyperexcitability of animals caused by caffeine. Osthole does not take part in the benzodiazepine binding site, since its effect is not inhibited by flumazenil at a concentration of 1 μm. A possible mechanism of action of osthole is interaction with GABA receptors. Osthole, like Imperatorin and Cnidiline, is able to enhance the effect of chloride flux provoked by GABA activation by 273.6%±39.4% (Osthole), 109.8%±37.7% (Imperatorin) and by 204.5%±33.2% (Cnidiline). Studies of the drug were carried out only at its concentration of 100 microns and 300 microns, the above results were obtained at 300 microns. Apparently, they can vary depending on the dosage. This effect was observed in association with the α1β2γ2S GABA subset, with an EC50 osthole value of 14+/-1µm. By itself, cayenne root, at doses of 50 to 500mg/kg, does not sedate allergic rats (see section on allergies).

Protective effect

Zhgun-root is able to prevent spatial orientation disorders in rats, which can be observed as a result of either oophorectomy or oral administration of 3-10 mg/kg of scopolamine.

Interaction with glucose metabolism

skeletal muscles

Osthole, depending on the dosage and time, enhances the absorption of glucose by myocytes (both C2C12 and L6), which occurs under the influence of AMPK. The concentration of the drug in this study remained in the range of 12.5-50 microns, although it affects hepatocytes at a lower amount. Incubation of muscle cells at 12.5 and 50 μm of the drug increases glucose uptake through GLUT4 translocation (which occurs under the influence of AMPK) by 1.6 or 2 times, respectively. AMPK can have such an effect by changing the ratio of AMP to ATP, which, in turn, contributes to osthole - lowering ATP, it increases AMP, and this, as you know, is the main stimulator of AMPK in skeletal muscles. Osthol, in vivo, and at a concentration of 50 mg/kg, showed anti-glycemic properties even before its relationship with AMPK was discovered. This experiment was replicated in mice induced with streptozotocin for diabetes by oral administration of 100mg/kg osthole for 8 weeks and found the same antiglycemic effect. Apparently, osthole can also phosphorylate (activate) protein kinase B and decrease the concentration of AS160 and GSK3 proteins, another possible mechanism for increasing GLUT4.

Fat

Similarly, AMPK can be activated in adipocytes due to the increased degree of adipocyte differentiation in rats following oral administration of 50mg/kg osthol. This is considered an anti-diabetic property, as more cells begin to absorb glucose.

Interaction with the liver

Osthole may have an anti-diabetic effect in people with fatty liver due to its ability to slow down its development. Oral ingestion of 5-10mg/kg osthole can lower hepatic fatty acid and triglyceride levels in addition to its anti-inflammatory effects, which increases insulin sensitivity in obese animals.

Interaction with obesity

rAPPα/γ

Osthole is a mixed rAPP alpha and gamma activity stimulant, which is one of the mechanisms of action that fight fatty liver. The same mechanism has been suggested for antidiabetic effects, but AMPK activation seems to be the more likely explanation. Activation of rAPPα and rAPPγ is a fat-burning mechanism that is triggered by the intake of certain nutritional supplements, such as conjugated lionelic acid and, more effectively, TTK. Thus, osthole has the potential to be a fat-burning agent. Studies in rats to measure body weight did not show significant results. Mice were fed a diet that caused fatty infiltration of the liver and, if they usually gained 9.5% of their weight, then the decrease was only 3.2-5.1%, regardless of the dosage of the drug. Potentially can either promote weight loss or prevent obesity (respectively, either reduce weight or prevent weight gain), but neither statement has yet been investigated

Impact on sexuality

Erection

Root Monnieri is a herbal preparation that is often prescribed by Chinese doctors for male impotence. It is traditionally used to increase male erection (or restore it) along with epimedium sagittate (a subspecies of Goryanka) and camelina sowing. In laboratory studies of the cavernous body, the bioactive component of osthole (at a certain dosage) was able to induce muscle relaxation. It is likely that this mechanism of action occurs through phosphodiesterase inhibition, since osthole (as well as nitric oxide) stimulates cGMP, which in turn causes muscle relaxation. This property is inherent in all coumarins in the Monnieri root, however, for an effective effect, emperorin requires the lowest concentration. This may also apply to brain function, as osthole promotes glutaminergic neurotransmission (see Neurology section). Although no human studies have been conducted, the drug is traditionally used in Chinese traditional medicine to increase erection and, like Viagra, effectively affects both the tissues of the penis and the brain.

Interaction with hormones

Testosterone

In one study, osthole increased testosterone levels and also luteinized the hormone and FSH in male rats for up to 20 days after castration. No further studies have been conducted.

Estrogen

In a study of ovariectomized rats (a research model of menopause), injections of 30mcg/kg of 17β-estradiol (a biologically active estrogen) and oral administration of 9mg/kg of osthole significantly reduced bone loss. However, in this study, it was noted that osthole does not affect other characteristics of estrogen metabolism and does not have an anti-osteoporotic effect on it. Ostol had no effect on the processes of reducing the body of the uterus and weight gain, which 17β-estradiol can slow down.

Progesterone

In a laboratory study of angelica chinensis along with monnieri rota, it was found that together they increase the production of progesterone in the corpus luteum.

Impact on allergies

Airways

Leather

The fruits of the zhgun-root are traditionally used as an anti-allergen. By interacting with various herbs (total n=33, it is effective already at 6), cayenne root is able to neutralize skin irritation, being the most effective drug for eliminating itching in mice caused by substance P. Oral intake of 50-500 mg / kg of ethanol extract Monnieri Root Burner neutralized the desire of mice to scratch irritated skin, suggesting its antipruritic effect. The same effect is observed after taking the fruits of the zhgun-root. The bioactive components are osthole and related coumarins such as isopimpinellin, while osthole (but not imperatorin) was effective on its own against compound 48/80, but only isopipinellin effectively counteracted substance P. Compared to diphenhydramine at 50mg/kg, cayenne root at 200mg/kg and 500mg/kg was less effective in neutralizing scratchy itchy skin, due to the fact that it caused a decrease of 33.1-34.7%, while diphenhydramine was 89.3% . Changing the dosage does not play a special role, since 50mg / kg had about the same effect as 200 and 500mg / kg. Coumarins, mostly isopipinellin, are effective in reducing skin irritation after oral ingestion as part of food or dietary supplements. Oral administration of 200-500mg/mg of osthole and coumarins to mice also suppressed contact dermatitis, which is associated with the inflammatory processes in question.

Zhgun-root to buy wholesale and retail with delivery in Moscow and Russia.

If you have problems with potency, tormented by a rash and itching, or you just feel a general breakdown, try using the herb zhgun-root, the healing effect of which was used already in the days of ancient Chinese medicine.

Zhgun-root is an umbrella herbaceous plant, the distribution halo of which is the Far Eastern region of Russia, as well as China, Mongolia, Korea and Japan. The positive effect of the tincture of the fruits of this plant on male power was known to Chinese healers already 2000 years ago. And since then, any Chinese knows that the secret of the rapid restoration of male potency lies in this small plant.

In addition, in Chinese medicine, powdered fruits of the root were used externally to cure skin diseases, different kind inflammation and rash, as well as itching of the genital organs.

To date, official medicine has fully confirmed the therapeutic effect of taking this plant. It is used as:

• Antibacterial;
• Antifungal;
• Tonic;
• Antipruritic;
• Stimulant;
• Expectorant.

As a medicinal raw material, the fruits of the plant are used, which are cut with a leg along with an umbrella and left to ripen and dry. Then they are threshed and sieved.

The fruits of the zhgun-root are often used in female gynecology. Regular intake of the tincture of the plant helps to restore the menstrual cycle, and its antibacterial properties cope well with inflammation in various gynecological diseases. In addition, it is an excellent prophylactic against breast cancer.

Due to its properties, it helps well in the treatment of diseases associated with various inflammatory processes in the human body:

• Rheumatism;
• Osteoporosis;
• Diseases of the stomach (gastritis, gastroenteritis, food poisoning). Taking the tincture relaxes smooth muscles, thereby relieving pain and normalizing the work of the gastrointestinal tract;
• Urolithiasis disease;
• Allergy.

In addition to using its therapeutic effect, zhgun-root can be taken as a general tonic, the regular use of which:

• Renders beneficial effect on the work of the heart;
• Increases immunity;
• Improves appetite.

And of course, the root burner remains the drug that helps relieve tension in the small pelvis, increases blood flow to it, as a result of which the time of sexual intercourse increases. The herb helps the production of sperm in the body of a man and accelerates its mobility. Therefore, it is taken in the treatment of impotence. There are enough recipes from this herb in folk medicine that help men and women restore reproductive strength and sexual energy. It is also an excellent natural aphrodisiac for men.

As with any medication, you should consult your doctor before taking it.

A long history of success

One of the most popular channels in Russia, Muz-TV, debuted on domestic television back in 1996. Despite its name, its main product was political broadcasting in support of the current government led by Boris Yeltsin. Over time, the channel's ideology changed and gradually its broadcasts were filled with entertainment programs.

Starting from 1997, it was broadcast in the same grid with 2x2, however, this television format did not last long and already in 1999 Muz-TV became a full-fledged round-the-clock channel.
During the year, the channel's broadcasting was limited exclusively to the capital region. The situation changed in 2001. Since that time, Muz-TV has been airing in most regions of the Russian Federation.

In 2001, at the PROMAX & BDA festival, this channel was awarded a prestigious television award, and a year later it becomes part of Igor Krutoy's ARS Records media holding. Currently 75% of the shares are owned Russian entrepreneur Alisher Usmanov.

In 2010, Muz-TV merged with the YuTV channel into a single media holding YuTV. Thus, a new entertainment channel for young people called “Yu” was founded, broadcasting programs in a new HD format.

Award History

During the peak of the channel's popularity, namely in 2003, Muz-TV established its own award, which to this day is one of the most prestigious awards in the field of Russian and foreign pop music.
In each of the existing nominations, the expert council selects five performers, who contest the title of the best among themselves. Voting and determination of victors takes place on the official portal of Muz-TV.

Honorary awards are presented to the winners as part of a solemn ceremony, which is held on the stage of the Olimpiysky Sports Complex in the presence of an audience of thousands, consisting of the most devoted fans of Russian and foreign performers.

The program of the ceremony has the format of a bright musical show, in the final of which real monsters of the world pop industry perform before the audience. Over the 15 years of the project's existence, such stars have performed on the stage of the Olimpiysky musical Olympus like "The Pussycat Dolls", "30 seconds to Mars", Cristina Aguilera, "50 Cent", Katy Perry, " Tokio Hotel”, “Sum 41”, Jennifer Lopez and many others.

Interesting facts of the ceremony "Muz-TV" 2017

The fifteenth anniversary ceremony of "Muz-TV", as always, took place in the capital's sports complex "Olympic". The honored guests of the award were:

• Polina Popova (Miss Russia 2017);
• Kelly Ann Hu (American model and actress);
• Andrea Boceli (Italian popular and classical music performer).

Four star representatives of Russian show business acted as hosts at once - Dmitry Nagiyev, Maxim Galkin, Ksenia Sobchak and Lena Kudryavtseva.

Voting took place in two successive stages. In the process of the first award expert jury selected the main nominees in all 15 categories. Each of them included six or more applicants.
At the second stage (as mentioned above), a general vote took place, in which, in addition to the professional jury, active users of the Muz-TV portal took part. It is worth recalling that the Internet voting started on April 13, 2017, which was announced in advance on the air of the channel.

Winners in the Muz-TV 2017 nominations:

• best performer: Timati (Russia);
• best performer: Svetlana Loboda (Ukraine);
• best pop group: Degrees (Russia);
• Best Album: Did You Love? (Ani Lorak);
• best duet: Nargiz and Max Fadeev ("Together");
• best hip-hop project: Mot (Russia);
• best rock artist: Nargiz (USA);
• best male video: “I like it” (Egor Creed);
• the best female video: "Kiss" (Nyusha);
• the best concert program: "I" (Philip Kirkorov);
• best single: "You are The Only One" (Sergey Lazarev);
• best song on foreign language: group "Silver" (Russia).

Date of the ceremony "Muz-TV" 2018

The music channel, beloved by millions of Russians, continues the tradition of awarding the best domestic and foreign performers. Due to the fact that the year has just begun, the contenders for the prize are still unknown. At the same time, the organizers of the event have already announced the date of the event. According to information published on the channel's portal, the award is scheduled for June 8, 2018. In addition, the participants of the final concert, who were invited as guests of honor, became known. Thus, Sergey Lazarev, Nyusha, Ani Lorak and Dmitry Bilan will perform in the final of the show program.

The Moscow SC Olimpiysky will traditionally be the venue for the Muz-TV channel ceremony. The only change in the format of the show will be its new name - "Muz-TV Award: Transformation". Given this innovation, we can confidently assume that the organizers of the show program have prepared a special surprise for the audience.

Official ticket sales at the Olimpiyskiy Sports Complex started last year, on December 25, 2017. Therefore, in order not to miss the most grandiose musical event of the year, you should hurry up, because there is not much time left before it.